Cross-Coupling of Aromatic Bromides with Allylic Silanolate Salts

Nickel-catalyzed cross-coupling reactions of benzylic zinc reagents with aromatic bromides, chlorides and tosylates.

Benzylic zinc reagents prepared by direct insertion of zinc to benzylic chlorides in the presence of LiCl undergo smooth cross-coupling reactions with aromatic chlorides, bromides and tosylates using Ni(acac)(2) and PPh(3) as a catalyst system.

Microwave-enhanced cross-coupling reactions involving alkynyltrifluoroborates with aryl bromides.

Palladium-catalyzed alkynylation has emerged as one of the most reliable methods for the synthesis of alkynes which are often used in natural product syntheses and material science. An efficient method for coupling alkynyltrifluoroborates with various aryl bromides in the presence of a palladium catalyst has been developed using microwave irradiation. The microwave reactions are rapid and effic...

Nickel-catalyzed reductive allylation of aryl bromides with allylic acetates.

This paper highlights Ni-catalyzed allylation of electron-rich aryl bromides with a variety of substituted allylic carbonates using zinc as the terminal reductant, affording E-alkenes regioselectively in good to excellent yields by the addition of aryl to the less hindered allylic carbon. The electron-deficient aryl bromides and chlorides are also highly efficient coupling partners.

Enantiospecific, regioselective cross-coupling reactions of secondary allylic boronic esters.

Spotlight: Imidazolium-based salts: With Y-aromatic counterions

Meysam Yarie was born in 1987 in Malayer/ Hamedan, Iran. He received his B.Sc. in Applied Chemistry from Malek-Ashtar University of Technology and M.Sc. in Organic Chemistry from Kurdistan University under the supervision of Dr. Kamal Amani. He received his Ph.D. from Bu-Ali Sina University under the supervision of Professor Mohammad Ali Zolfigol. He is currently working towards his Post-Doctor...